Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7923.016 | 0.5426 | -0.2446 | 0.6280 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7923.016 | 0.5953 | -0.1245 | 0.6280 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7923.016 | 0.5582 | -0.2097 | 0.6280 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7923.016 | 0.5362 | -0.2587 | 0.6280 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7923.016 | 0.6676 | 0.0511 | 0.6280 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7923.016 | 0.1676 | -0.8836 | 0.6280 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 9878.019 | 0.9751 | 0.9662 | 1.4790 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 9878.019 | 0.9590 | 0.9442 | 1.4790 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 9878.019 | 0.9768 | 0.9685 | 1.4790 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 9878.019 | 1.0062 | 1.0083 | 1.4790 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 9878.019 | 0.9982 | 0.9976 | 1.4790 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 9878.019 | 0.9773 | 0.9692 | 1.4790 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 9878.019 | 0.8688 | 0.8186 | 1.4790 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 9878.019 | 0.9655 | 0.9531 | 1.4790 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 9878.019 | 0.7603 | 0.6618 | 1.4790 | |
| T47D | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 9033.016 | 0.9253 | 0.8901 | 1.3741 | |
| T47D | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 9033.016 | 0.9093 | 0.8663 | 1.3741 | |
| T47D | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 9033.016 | 1.0226 | 1.0327 | 1.3741 | |
| T47D | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 9033.016 | 0.9587 | 0.9395 | 1.3741 | |
| T47D | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 9033.016 | 0.9156 | 0.8756 | 1.3741 | |
| T47D | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 9033.016 | 0.9572 | 0.9374 | 1.3741 | |
| T47D | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 9033.016 | 0.8179 | 0.7277 | 1.3741 | |
| T47D | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 9033.016 | 0.5896 | 0.3616 | 1.3741 | |
| T47D | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 9033.016 | 0.6099 | 0.3957 | 1.3741 | |
| UACC-893 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 9045.016 | 1.0696 | 1.1549 | 0.9026 |