Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12400.168 | 0.9944 | 0.9915 | 1.3275 | |
| HCC70 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12400.168 | 1.0158 | 1.0237 | 1.3275 | |
| HCC70 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12400.168 | 0.9889 | 0.9832 | 1.3275 | |
| HCC70 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 33.3 | uM | 12400.168 | 0.9387 | 0.9069 | 1.3275 | |
| HCC70 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 167 | uM | 12400.168 | 0.9639 | 0.9454 | 1.3275 | |
| Hs 578T | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10694.144 | 1.1816 | 1.1603 | 2.1636 | |
| Hs 578T | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10694.144 | 1.1434 | 1.1278 | 2.1636 | |
| Hs 578T | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10694.144 | 1.2468 | 1.2147 | 2.1636 | |
| Hs 578T | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10694.144 | 1.1403 | 1.1251 | 2.1636 | |
| Hs 578T | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10694.144 | 1.1794 | 1.1585 | 2.1636 | |
| Hs 578T | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10694.144 | 1.1633 | 1.1449 | 2.1636 | |
| Hs 578T | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 4 | uM | 10694.144 | 1.1061 | 1.0954 | 2.1636 | |
| Hs 578T | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 20 | uM | 10694.144 | 0.8628 | 0.8681 | 2.1636 | |
| Hs 578T | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 100 | uM | 10694.144 | 0.2963 | 0.1399 | 2.1636 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10816.144 | 1.0379 | 1.0831 | 0.9146 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10816.144 | 1.0641 | 1.1407 | 0.9146 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10816.144 | 1.0769 | 1.1688 | 0.9146 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10816.144 | 1.0048 | 1.0104 | 0.9146 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10816.144 | 0.9569 | 0.9059 | 0.9146 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10816.144 | 1.0808 | 1.1773 | 0.9146 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 10816.144 | 1.0776 | 1.1702 | 0.9146 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 10816.144 | 0.9750 | 0.9453 | 0.9146 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 10816.144 | 1.0021 | 1.0045 | 0.9146 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000427 | uM | 12319.168 | 0.8905 | 0.7716 | 0.9560 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00213 | uM | 12319.168 | 0.9227 | 0.8385 | 0.9560 |