Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 4 | uM | 10581.144 | 0.8819 | 0.8019 | 1.2048 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 20 | uM | 10581.144 | 0.8757 | 0.7913 | 1.2048 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 100 | uM | 10581.144 | 0.8807 | 0.7998 | 1.2048 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 11854.144 | 0.9668 | 0.9492 | 1.3102 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 11854.144 | 1.0369 | 1.0561 | 1.3102 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 11854.144 | 0.9640 | 0.9449 | 1.3102 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 11854.144 | 1.0856 | 1.1294 | 1.3102 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 11854.144 | 0.9421 | 0.9109 | 1.3102 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 11854.144 | 0.9821 | 0.9726 | 1.3102 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 4 | uM | 11854.144 | 0.9711 | 0.9557 | 1.3102 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 20 | uM | 11854.144 | 0.8333 | 0.7402 | 1.3102 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 100 | uM | 11854.144 | 0.3729 | -0.0581 | 1.3102 | |
| BT-474 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 12056.144 | 0.9526 | 0.9028 | 0.9738 | |
| BT-474 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 12056.144 | 0.9111 | 0.8177 | 0.9738 | |
| BT-474 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 12056.144 | 0.9629 | 0.9239 | 0.9738 | |
| BT-474 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 12056.144 | 0.9963 | 0.9924 | 0.9738 | |
| BT-474 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 12056.144 | 0.8991 | 0.7931 | 0.9738 | |
| BT-474 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 12056.144 | 0.9219 | 0.8398 | 0.9738 | |
| BT-474 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 12056.144 | 0.9110 | 0.8174 | 0.9738 | |
| BT-474 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 12056.144 | 0.8927 | 0.7799 | 0.9738 | |
| BT-474 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 12056.144 | 0.8586 | 0.7102 | 0.9738 | |
| BT-474 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 12178.144 | 0.9305 | 0.8254 | 0.7891 | |
| BT-474 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 12178.144 | 0.9167 | 0.7913 | 0.7891 | |
| BT-474 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 12178.144 | 0.9062 | 0.7652 | 0.7891 | |
| BT-474 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 12178.144 | 0.9598 | 0.8988 | 0.7891 |