Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | SB-3CT | MMP2/9 | MMP | 167 | uM | 12566.168 | 0.9020 | 0.8615 | 1.4366 | |
| 600MPE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 12224.144 | 0.9231 | 0.8493 | 1.0210 | |
| 600MPE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 12224.144 | 0.9209 | 0.8450 | 1.0210 | |
| 600MPE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 12224.144 | 0.9420 | 0.8864 | 1.0210 | |
| 600MPE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 12224.144 | 0.9401 | 0.8827 | 1.0210 | |
| 600MPE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 12224.144 | 0.9193 | 0.8418 | 1.0210 | |
| 600MPE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 12224.144 | 0.9063 | 0.8163 | 1.0210 | |
| 600MPE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 12224.144 | 0.9687 | 0.9387 | 1.0210 | |
| 600MPE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 12224.144 | 0.9205 | 0.8442 | 1.0210 | |
| 600MPE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 12224.144 | 0.9227 | 0.8485 | 1.0210 | |
| AU565 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10880.144 | 0.8979 | 0.8870 | 1.8532 | |
| AU565 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10880.144 | 0.9619 | 0.9585 | 1.8532 | |
| AU565 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10880.144 | 0.9126 | 0.9037 | 1.8532 | |
| AU565 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10880.144 | 0.9900 | 0.9891 | 1.8532 | |
| AU565 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10880.144 | 0.9086 | 0.8991 | 1.8532 | |
| AU565 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10880.144 | 0.9382 | 0.9324 | 1.8532 | |
| AU565 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 10880.144 | 0.9872 | 0.9862 | 1.8532 | |
| AU565 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 10880.144 | 0.8942 | 0.8829 | 1.8532 | |
| AU565 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 10880.144 | 0.7259 | 0.6825 | 1.8532 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10581.144 | 1.0075 | 1.0125 | 1.2048 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10581.144 | 0.8796 | 0.7979 | 1.2048 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10581.144 | 0.9890 | 0.9817 | 1.2048 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10581.144 | 0.8882 | 0.8125 | 1.2048 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10581.144 | 0.9653 | 0.9423 | 1.2048 | |
| BT-20 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10581.144 | 0.9459 | 0.9098 | 1.2048 |