Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.000427 | uM | 12000.155 | 0.9383 | 0.8570 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.000427 | uM | 12000.155 | 0.9383 | 0.8570 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.00213 | uM | 12000.155 | 0.9407 | 0.8626 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.00213 | uM | 12000.155 | 0.9407 | 0.8626 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.0107 | uM | 12000.155 | 0.9109 | 0.7941 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.0107 | uM | 12000.155 | 0.9109 | 0.7941 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.0533 | uM | 12000.155 | 0.9606 | 0.9085 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.0533 | uM | 12000.155 | 0.9606 | 0.9085 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.267 | uM | 12000.155 | 0.9125 | 0.7978 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.267 | uM | 12000.155 | 0.9125 | 0.7978 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 1.33 | uM | 12000.155 | 0.8817 | 0.7274 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 1.33 | uM | 12000.155 | 0.8817 | 0.7274 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 6.67 | uM | 12000.155 | 0.9083 | 0.7882 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 6.67 | uM | 12000.155 | 0.9083 | 0.7882 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 33.3 | uM | 12000.155 | 0.8739 | 0.7096 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 33.3 | uM | 12000.155 | 0.8739 | 0.7096 | 0.8592 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.0000853 | uM | 12084.155 | 0.9856 | 0.9777 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.0000853 | uM | 12084.155 | 0.9856 | 0.9777 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.000427 | uM | 12084.155 | 0.9792 | 0.9678 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.000427 | uM | 12084.155 | 0.9792 | 0.9678 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.00213 | uM | 12084.155 | 1.0676 | 1.1036 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.00213 | uM | 12084.155 | 1.0676 | 1.1036 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.0107 | uM | 12084.155 | 0.9613 | 0.9400 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.0107 | uM | 12084.155 | 0.9613 | 0.9400 | 1.2955 | |
| HCC1395 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.0533 | uM | 12084.155 | 1.0532 | 1.0816 | 1.2955 |