Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 12056.155 | 0.8612 | 0.6687 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 12056.155 | 0.8612 | 0.6687 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 12056.155 | 0.8779 | 0.7079 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 12056.155 | 0.8779 | 0.7079 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 12056.155 | 0.9907 | 0.9775 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 12056.155 | 0.9907 | 0.9775 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12056.155 | 0.9627 | 0.9100 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12056.155 | 0.9627 | 0.9100 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 12056.155 | 0.9671 | 0.9205 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 12056.155 | 0.9671 | 0.9205 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 12056.155 | 0.9148 | 0.7953 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 12056.155 | 0.9148 | 0.7953 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 12056.155 | 0.9072 | 0.7773 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 12056.155 | 0.9072 | 0.7773 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12056.155 | 0.8246 | 0.5832 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12056.155 | 0.8246 | 0.5832 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12056.155 | 0.8614 | 0.6691 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12056.155 | 0.8614 | 0.6691 | 0.8251 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 12178.155 | 0.9188 | 0.8100 | 0.8489 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 12178.155 | 0.9188 | 0.8100 | 0.8489 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 12178.155 | 0.8945 | 0.7539 | 0.8489 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 12178.155 | 0.8945 | 0.7539 | 0.8489 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 12178.155 | 0.8589 | 0.6719 | 0.8489 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 12178.155 | 0.8589 | 0.6719 | 0.8489 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12178.155 | 0.8974 | 0.7604 | 0.8489 |