Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7547.093 | 0.8920 | 0.8040 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7547.093 | 0.9433 | 0.8975 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7547.093 | 0.8803 | 0.7827 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7547.093 | 0.9318 | 0.8766 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7547.093 | 0.8005 | 0.6363 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7547.093 | 0.0153 | -0.9539 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 10420.093 | 1.0175 | 1.0626 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 10420.093 | 1.0335 | 1.1204 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 10420.093 | 0.9157 | 0.7102 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 10420.093 | 0.9353 | 0.7759 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 10420.093 | 1.0080 | 1.0286 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 10420.093 | 0.9879 | 0.9574 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 10420.093 | 0.9358 | 0.7776 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 10420.093 | 0.8502 | 0.4990 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 10420.093 | 0.3770 | -0.6464 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 10580.1 | 0.9985 | 0.9963 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 10580.1 | 0.8993 | 0.7505 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 10580.1 | 0.9212 | 0.8042 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 10580.1 | 0.8641 | 0.6650 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 10580.1 | 0.9510 | 0.8777 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 10580.1 | 0.8991 | 0.7502 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 10580.1 | 0.9172 | 0.7945 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 10580.1 | 0.7919 | 0.4922 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 66.7 | uM | 10580.1 | 0.0139 | -0.9907 | 0.7968 | |
| ZR-75-1 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7553.093 | 0.9678 | 0.9435 | 1.1429 |