Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MDA-MB-175-VII
HR+
Luminal
Nelfinavir
0.267
uM
13754.174
0.9227 0.6579 0.4290
MDA-MB-175-VII
HR+
Luminal
Nelfinavir
1.33
uM
13754.174
0.9481 0.7664 0.4290
MDA-MB-175-VII
HR+
Luminal
Nelfinavir
6.67
uM
13754.174
0.8809 0.4883 0.4290
MDA-MB-175-VII
HR+
Luminal
Nelfinavir
33.3
uM
13754.174
0.1518 -0.9753 0.4290
MDA-MB-361
HER2amp
Luminal
Nelfinavir
0.0000853
uM
12989.174
0.9812 0.9471 0.7084
MDA-MB-361
HER2amp
Luminal
Nelfinavir
0.000427
uM
12989.174
0.8622 0.6224 0.7084
MDA-MB-361
HER2amp
Luminal
Nelfinavir
0.00213
uM
12989.174
0.9862 0.9610 0.7084
MDA-MB-361
HER2amp
Luminal
Nelfinavir
0.0107
uM
12989.174
1.0166 1.0470 0.7084
MDA-MB-361
HER2amp
Luminal
Nelfinavir
0.0533
uM
12989.174
1.0070 1.0197 0.7084
MDA-MB-361
HER2amp
Luminal
Nelfinavir
0.267
uM
12989.174
0.9840 0.9551 0.7084
MDA-MB-361
HER2amp
Luminal
Nelfinavir
1.33
uM
12989.174
0.9563 0.8778 0.7084
MDA-MB-361
HER2amp
Luminal
Nelfinavir
6.67
uM
12989.174
0.8350 0.5505 0.7084
MDA-MB-361
HER2amp
Luminal
Nelfinavir
33.3
uM
12989.174
0.0365 -0.9813 0.7084
MDA-MB-361
HER2amp
Luminal
Nelfinavir
0.0000853
uM
13558.174
0.9788 0.9262 0.5699
MDA-MB-361
HER2amp
Luminal
Nelfinavir
0.000427
uM
13558.174
0.9624 0.8698 0.5699
MDA-MB-361
HER2amp
Luminal
Nelfinavir
0.00213
uM
13558.174
0.9299 0.7604 0.5699
MDA-MB-361
HER2amp
Luminal
Nelfinavir
0.0107
uM
13558.174
0.9726 0.9047 0.5699
MDA-MB-361
HER2amp
Luminal
Nelfinavir
0.0533
uM
13558.174
0.9894 0.9628 0.5699
MDA-MB-361
HER2amp
Luminal
Nelfinavir
0.267
uM
13558.174
0.9499 0.8276 0.5699
MDA-MB-361
HER2amp
Luminal
Nelfinavir
1.33
uM
13558.174
0.9861 0.9516 0.5699
MDA-MB-361
HER2amp
Luminal
Nelfinavir
6.67
uM
13558.174
0.9245 0.7427 0.5699
MDA-MB-361
HER2amp
Luminal
Nelfinavir
33.3
uM
13558.174
1.0050 1.0176 0.5699
MDA-MB-415
HR+
Luminal
Nelfinavir
0.0000853
uM
12959.174
0.9728 0.8930 0.5020
MDA-MB-415
HR+
Luminal
Nelfinavir
0.000427
uM
12959.174
0.9436 0.7815 0.5020
MDA-MB-415
HR+
Luminal
Nelfinavir
0.00213
uM
12959.174
0.9738 0.8969 0.5020