Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10818.145 | 0.3822 | -0.7504 | 0.4621 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10818.145 | 0.3822 | -0.7504 | 0.4621 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10818.145 | 0.0773 | -0.9922 | 0.4621 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10818.145 | 0.0773 | -0.9922 | 0.4621 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10818.145 | 0.0372 | -0.9984 | 0.4621 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10818.145 | 0.0372 | -0.9984 | 0.4621 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10818.145 | 0.0281 | -0.9991 | 0.4621 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10818.145 | 0.0281 | -0.9991 | 0.4621 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12126.145 | 1.0155 | 1.0479 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12126.145 | 1.0155 | 1.0479 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12126.145 | 0.9413 | 0.8220 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12126.145 | 0.9413 | 0.8220 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12126.145 | 0.9779 | 0.9322 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12126.145 | 0.9779 | 0.9322 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12126.145 | 0.9720 | 0.9143 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12126.145 | 0.9720 | 0.9143 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12126.145 | 0.9686 | 0.9041 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12126.145 | 0.9686 | 0.9041 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12126.145 | 0.2233 | -0.8013 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12126.145 | 0.2233 | -0.8013 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12126.145 | 0.0267 | -0.9924 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12126.145 | 0.0267 | -0.9924 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12126.145 | 0.0244 | -0.9934 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12126.145 | 0.0244 | -0.9934 | 0.6493 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12126.145 | 0.0222 | -0.9943 | 0.6493 |