Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14161.189 | 0.0231 | -0.9349 | 1.1003 | |
| MCF 10F | NM | - | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14161.189 | 0.0231 | -0.9349 | 1.1003 | |
| MCF 10F | NM | - | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14161.189 | 0.0244 | -0.9316 | 1.1003 | |
| MCF 10F | NM | - | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14161.189 | 0.0244 | -0.9316 | 1.1003 | |
| MCF 10F | NM | - | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14161.189 | 0.4969 | 0.0591 | 1.1003 | |
| MCF 10F | NM | - | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14161.189 | 0.4969 | 0.0591 | 1.1003 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10817.145 | 0.9619 | 0.9507 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10817.145 | 0.9619 | 0.9507 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10817.145 | 0.9443 | 0.9277 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10817.145 | 0.9443 | 0.9277 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10817.145 | 1.0090 | 1.0116 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10817.145 | 1.0090 | 1.0116 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10817.145 | 0.9647 | 0.9544 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10817.145 | 0.9647 | 0.9544 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10817.145 | 0.1961 | -0.2979 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10817.145 | 0.1961 | -0.2979 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10817.145 | 0.0956 | -0.5574 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10817.145 | 0.0956 | -0.5574 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10817.145 | 0.0202 | -0.8372 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10817.145 | 0.0202 | -0.8372 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10817.145 | 0.0195 | -0.8404 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10817.145 | 0.0195 | -0.8404 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10817.145 | 0.0159 | -0.8603 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10817.145 | 0.0159 | -0.8603 | 1.5564 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12365.17 | 0.9132 | 0.9223 | 2.2930 |