Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14200.189 | 1.0289 | 1.0174 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14200.189 | 1.0289 | 1.0174 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14200.189 | 0.9952 | 0.9971 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14200.189 | 0.9952 | 0.9971 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14200.189 | 0.6052 | 0.7174 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14200.189 | 0.6052 | 0.7174 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14200.189 | 0.0003 | -0.8248 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14200.189 | 0.0003 | -0.8248 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14200.189 | 0.0003 | -0.8248 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14200.189 | 0.0003 | -0.8248 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14200.189 | 0.0029 | -0.6589 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14200.189 | 0.0029 | -0.6589 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14200.189 | 1.0697 | 1.0413 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14200.189 | 1.0697 | 1.0413 | 3.2969 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10755.145 | 1.0247 | 1.0644 | 0.7688 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10755.145 | 1.0247 | 1.0644 | 0.7688 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10755.145 | 0.9179 | 0.7892 | 0.7688 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10755.145 | 0.9179 | 0.7892 | 0.7688 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10755.145 | 0.9658 | 0.9115 | 0.7688 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10755.145 | 0.9658 | 0.9115 | 0.7688 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10755.145 | 0.9530 | 0.8786 | 0.7688 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10755.145 | 0.9530 | 0.8786 | 0.7688 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10755.145 | 0.9389 | 0.8425 | 0.7688 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10755.145 | 0.9389 | 0.8425 | 0.7688 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10755.145 | 0.2119 | -0.7342 | 0.7688 |