Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 5900.066 | 1.0116 | 1.0085 | 2.7232 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 5900.066 | 0.9064 | 0.9291 | 2.7232 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 5900.066 | 0.8485 | 0.8829 | 2.7232 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 5901.066 | 0.9765 | 0.9757 | 1.9445 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 5901.066 | 0.9737 | 0.9727 | 1.9445 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 5901.066 | 0.9890 | 0.9886 | 1.9445 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 5901.066 | 1.0079 | 1.0081 | 1.9445 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 5901.066 | 0.9930 | 0.9928 | 1.9445 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 5901.066 | 0.9777 | 0.9769 | 1.9445 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 5901.066 | 1.0225 | 1.0230 | 1.9445 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 5901.066 | 0.9540 | 0.9521 | 1.9445 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 5901.066 | 0.8717 | 0.8636 | 1.9445 | |
| BT-20 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 5902.066 | 1.0754 | 1.1273 | 1.1775 | |
| BT-20 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 5902.066 | 0.9867 | 0.9773 | 1.1775 | |
| BT-20 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 5902.066 | 1.0411 | 1.0695 | 1.1775 | |
| BT-20 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 5902.066 | 0.9993 | 0.9988 | 1.1775 | |
| BT-20 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 5902.066 | 1.0511 | 1.0865 | 1.1775 | |
| BT-20 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 5902.066 | 1.0086 | 1.0146 | 1.1775 | |
| BT-20 | TNBC | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 5902.066 | 1.0301 | 1.0510 | 1.1775 | |
| BT-20 | TNBC | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 5902.066 | 0.9994 | 0.9990 | 1.1775 | |
| BT-20 | TNBC | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 5902.066 | 1.0271 | 1.0459 | 1.1775 | |
| BT-20 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 5903.066 | 0.9729 | 0.9545 | 1.1945 | |
| BT-20 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 5903.066 | 0.9530 | 0.9210 | 1.1945 | |
| BT-20 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 5903.066 | 1.0087 | 1.0145 | 1.1945 | |
| BT-20 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 5903.066 | 1.0288 | 1.0481 | 1.1945 |