Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | AG1024 | IGF1R | RTK | 33.3 | uM | 5897.066 | 0.3251 | -0.1723 | 1.2737 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 5898.066 | 1.0149 | 1.0490 | 0.6097 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 5898.066 | 0.9652 | 0.8870 | 0.6097 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 5898.066 | 0.9996 | 0.9987 | 0.6097 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 5898.066 | 0.9743 | 0.9164 | 0.6097 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 5898.066 | 0.9882 | 0.9615 | 0.6097 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 5898.066 | 0.9595 | 0.8689 | 0.6097 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 5898.066 | 1.0224 | 1.0740 | 0.6097 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 5898.066 | 1.0128 | 1.0423 | 0.6097 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 5898.066 | 1.0184 | 1.0608 | 0.6097 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 5899.066 | 1.0158 | 1.0449 | 0.7056 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 5899.066 | 0.9727 | 0.9232 | 0.7056 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 5899.066 | 1.0256 | 1.0728 | 0.7056 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 5899.066 | 1.0343 | 1.0980 | 0.7056 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 5899.066 | 0.9510 | 0.8624 | 0.7056 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 5899.066 | 0.9961 | 0.9891 | 0.7056 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 5899.066 | 0.9630 | 0.8958 | 0.7056 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 5899.066 | 1.0865 | 1.2496 | 0.7056 | |
| 600MPE | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 5899.066 | 1.1561 | 1.4564 | 0.7056 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 5900.066 | 1.0491 | 1.0355 | 2.7232 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 5900.066 | 1.0101 | 1.0074 | 2.7232 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 5900.066 | 0.9888 | 0.9917 | 2.7232 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 5900.066 | 1.0423 | 1.0307 | 2.7232 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 5900.066 | 0.9995 | 0.9996 | 2.7232 | |
| AU565 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 5900.066 | 0.9929 | 0.9948 | 2.7232 |