Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 11852.154 | 1.0515 | 1.0799 | 1.2816 | |
| SUM52PE | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 11852.154 | 1.0690 | 1.1069 | 1.2816 | |
| SUM52PE | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 11852.154 | 1.0352 | 1.0547 | 1.2816 | |
| SUM52PE | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 11852.154 | 0.7947 | 0.6718 | 1.2816 | |
| SUM52PE | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 11852.154 | 0.5083 | 0.1796 | 1.2816 | |
| SUM52PE | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 11852.154 | 0.4469 | 0.0668 | 1.2816 | |
| SUM52PE | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 11852.154 | 0.1862 | -0.4613 | 1.2816 | |
| SUM52PE | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 11852.154 | 0.0113 | -0.9393 | 1.2816 | |
| T47D | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 10939.154 | 0.9321 | 0.9184 | 1.6876 | |
| T47D | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 10939.154 | 0.9645 | 0.9576 | 1.6876 | |
| T47D | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 10939.154 | 0.9984 | 0.9981 | 1.6876 | |
| T47D | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 10939.154 | 0.9758 | 0.9711 | 1.6876 | |
| T47D | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 10939.154 | 0.9680 | 0.9619 | 1.6876 | |
| T47D | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 10939.154 | 1.0702 | 1.0821 | 1.6876 | |
| T47D | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 10939.154 | 0.9545 | 0.9456 | 1.6876 | |
| T47D | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 10939.154 | 0.5621 | 0.4215 | 1.6876 | |
| T47D | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 10939.154 | 0.1726 | -0.2938 | 1.6876 | |
| T47DKBLUC | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 12608.167 | 1.0060 | 1.0094 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 12608.167 | 0.9826 | 0.9724 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 12608.167 | 0.9958 | 0.9933 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 12608.167 | 0.9869 | 0.9794 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 12608.167 | 1.0545 | 1.0855 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 12608.167 | 1.0643 | 1.1007 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 12608.167 | 1.1763 | 1.2733 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 12608.167 | 0.7410 | 0.5790 | 1.2681 |