Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 10997.154 | 1.0572 | 1.1039 | 1.0978 | |
| MCF7 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 10997.154 | 0.9987 | 0.9976 | 1.0978 | |
| MCF7 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 10997.154 | 0.9060 | 0.8279 | 1.0978 | |
| MCF7 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 10997.154 | 0.7731 | 0.5821 | 1.0978 | |
| MCF7 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 10997.154 | 0.0451 | -0.8812 | 1.0978 | |
| MCF7 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 10997.154 | 0.0223 | -0.9374 | 1.0978 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000256 | uM | 10519.142 | 0.9551 | 0.9001 | 0.8963 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00128 | uM | 10519.142 | 0.9454 | 0.8786 | 0.8963 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0064 | uM | 10519.142 | 0.9448 | 0.8773 | 0.8963 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.032 | uM | 10519.142 | 0.9365 | 0.8588 | 0.8963 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.16 | uM | 10519.142 | 0.7720 | 0.4985 | 0.8963 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.8 | uM | 10519.142 | 0.7784 | 0.5122 | 0.8963 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 4 | uM | 10519.142 | 0.6026 | 0.1366 | 0.8963 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 20 | uM | 10519.142 | 0.2051 | -0.6584 | 0.8963 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 100 | uM | 10519.142 | 0.0073 | -0.9918 | 0.8963 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 10998.154 | 0.9386 | 0.8362 | 0.7412 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 10998.154 | 1.0200 | 1.0541 | 0.7412 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 10998.154 | 0.9966 | 0.9907 | 0.7412 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 10998.154 | 0.9678 | 0.9135 | 0.7412 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 10998.154 | 0.9199 | 0.7870 | 0.7412 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 10998.154 | 0.8102 | 0.5056 | 0.7412 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 10998.154 | 0.6722 | 0.1702 | 0.7412 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 10998.154 | 0.4943 | -0.2270 | 0.7412 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 10998.154 | 0.1243 | -0.8800 | 0.7412 | |
| MDA-MB-134-VI | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 12206.154 | 0.9900 | 0.9803 | 1.0125 |