Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 100 | uM | 10642.142 | 0.6243 | -0.2198 | 0.5006 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 10818.154 | 0.9979 | 0.9918 | 0.5056 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 10818.154 | 0.9505 | 0.8088 | 0.5056 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 10818.154 | 0.9846 | 0.9394 | 0.5056 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 10818.154 | 0.9339 | 0.7470 | 0.5056 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 10818.154 | 0.9686 | 0.8777 | 0.5056 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 10818.154 | 0.9444 | 0.7859 | 0.5056 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 10818.154 | 0.7470 | 0.1233 | 0.5056 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 10818.154 | 0.2891 | -0.8282 | 0.5056 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 10818.154 | 0.7114 | 0.0199 | 0.5056 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 12126.154 | 0.9300 | 0.7725 | 0.6012 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 12126.154 | 0.8587 | 0.5524 | 0.6012 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 12126.154 | 0.9213 | 0.7451 | 0.6012 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 12126.154 | 0.9347 | 0.7876 | 0.6012 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 12126.154 | 0.8920 | 0.6536 | 0.6012 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 12126.154 | 0.8075 | 0.4015 | 0.6012 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 12126.154 | 0.5855 | -0.1791 | 0.6012 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 12126.154 | 0.1358 | -0.9278 | 0.6012 | |
| MDA-MB-175-VII | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 12126.154 | 0.4845 | -0.4008 | 0.6012 | |
| MDA-MB-361 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000256 | uM | 10643.142 | 1.0425 | 1.1677 | 0.5166 | |
| MDA-MB-361 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00128 | uM | 10643.142 | 0.9763 | 0.9094 | 0.5166 | |
| MDA-MB-361 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0064 | uM | 10643.142 | 0.9866 | 0.9484 | 0.5166 | |
| MDA-MB-361 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.032 | uM | 10643.142 | 0.9927 | 0.9718 | 0.5166 | |
| MDA-MB-361 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.16 | uM | 10643.142 | 0.8621 | 0.5006 | 0.5166 | |
| MDA-MB-361 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.8 | uM | 10643.142 | 0.6945 | -0.0125 | 0.5166 |