Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.0000853 | uM | 10642.137 | 1.0373 | 1.1145 | 0.6570 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.000427 | uM | 10642.137 | 0.9835 | 0.9499 | 0.6570 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.00213 | uM | 10642.137 | 0.9916 | 0.9743 | 0.6570 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.0107 | uM | 10642.137 | 1.0256 | 1.0785 | 0.6570 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.0533 | uM | 10642.137 | 1.0124 | 1.0378 | 0.6570 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.267 | uM | 10642.137 | 1.0050 | 1.0151 | 0.6570 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 1.33 | uM | 10642.137 | 1.0088 | 1.0268 | 0.6570 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 6.67 | uM | 10642.137 | 0.9377 | 0.8135 | 0.6570 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 33.3 | uM | 10642.137 | 0.6837 | 0.1213 | 0.6570 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.0000853 | uM | 10818.149 | 0.9945 | 0.9739 | 0.4210 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.000427 | uM | 10818.149 | 0.9315 | 0.6899 | 0.4210 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.00213 | uM | 10818.149 | 0.9941 | 0.9721 | 0.4210 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.0107 | uM | 10818.149 | 0.9950 | 0.9763 | 0.4210 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.0533 | uM | 10818.149 | 0.9718 | 0.8686 | 0.4210 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.267 | uM | 10818.149 | 0.9754 | 0.8849 | 0.4210 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 1.33 | uM | 10818.149 | 0.9787 | 0.9002 | 0.4210 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 6.67 | uM | 10818.149 | 0.8591 | 0.3941 | 0.4210 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 33.3 | uM | 10818.149 | 0.7083 | -0.1184 | 0.4210 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.000128 | uM | 12126.161 | 0.9657 | 0.8910 | 0.6227 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.00064 | uM | 12126.161 | 0.9102 | 0.7196 | 0.6227 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.0032 | uM | 12126.161 | 0.9175 | 0.7416 | 0.6227 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.016 | uM | 12126.161 | 0.8773 | 0.6209 | 0.6227 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.08 | uM | 12126.161 | 0.8864 | 0.6479 | 0.6227 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 0.4 | uM | 12126.161 | 0.9456 | 0.8283 | 0.6227 | |
MDA-MB-175-VII | HR+ | Luminal | L-779450 | BRAF | MAPK | 2 | uM | 12126.161 | 0.8822 | 0.6353 | 0.6227 |