Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7492.095 | 1.2171 | 1.4252 | 1.0194 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7492.095 | 1.3676 | 1.7190 | 1.0194 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7492.095 | 0.9582 | 0.9180 | 1.0194 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7492.095 | 1.3208 | 1.6278 | 1.0194 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7493.095 | 0.8363 | 0.6753 | 1.0092 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7493.095 | 0.6913 | 0.3873 | 1.0092 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7493.095 | 0.5199 | 0.0461 | 1.0092 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7493.095 | 0.4592 | -0.0751 | 1.0092 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7493.095 | 0.4099 | -0.1735 | 1.0092 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7493.095 | 0.3766 | -0.2400 | 1.0092 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7493.095 | 0.3558 | -0.2817 | 1.0092 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7493.095 | 0.4579 | -0.0776 | 1.0092 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7493.095 | 0.0017 | -0.9964 | 1.0092 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7494.094 | 0.8592 | 0.7130 | 0.9794 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00253 | uM | 7494.094 | 0.4837 | -0.0472 | 0.9794 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7494.094 | 0.4341 | -0.1470 | 0.9794 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0632 | uM | 7494.094 | 0.4305 | -0.1543 | 0.9794 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7494.094 | 0.3984 | -0.2184 | 0.9794 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7494.094 | 0.5269 | 0.0397 | 0.9794 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7494.094 | 0.3515 | -0.3122 | 0.9794 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.5 | uM | 7494.094 | 0.0072 | -0.9870 | 0.9794 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 197 | uM | 7494.094 | 0.0062 | -0.9888 | 0.9794 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 10419.095 | 0.9834 | 0.9558 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 10419.095 | 0.9296 | 0.8145 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 10419.095 | 0.7947 | 0.4724 | 0.7505 |