Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7457.094 | 0.0652 | -0.5442 | 1.8462 | |
| HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7457.094 | 0.0256 | -0.7252 | 1.8462 | |
| HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 39.5 | uM | 7457.094 | 0.0043 | -0.8956 | 1.8462 | |
| HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 197 | uM | 7457.094 | 0.0392 | -0.6538 | 1.8462 | |
| HCC202 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7458.095 | 1.0080 | 1.0430 | 0.3752 | |
| HCC202 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7458.095 | 1.0091 | 1.0491 | 0.3752 | |
| HCC202 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7458.095 | 0.9929 | 0.9622 | 0.3752 | |
| HCC202 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7458.095 | 0.6968 | -0.2364 | 0.3752 | |
| HCC202 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7458.095 | 0.3705 | -0.8582 | 0.3752 | |
| HCC202 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7458.095 | 0.3530 | -0.8754 | 0.3752 | |
| HCC202 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7458.095 | 0.3769 | -0.8516 | 0.3752 | |
| HCC202 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7458.095 | 0.1882 | -0.9767 | 0.3752 | |
| HCC202 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7458.095 | 0.0048 | -1.0000 | 0.3752 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7462.095 | 1.0137 | 1.0720 | 0.3840 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7462.095 | 1.0054 | 1.0282 | 0.3840 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7462.095 | 0.9809 | 0.9022 | 0.3840 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7462.095 | 0.7888 | 0.0782 | 0.3840 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7462.095 | 0.4694 | -0.7209 | 0.3840 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7462.095 | 0.4021 | -0.8135 | 0.3840 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7462.095 | 0.5946 | -0.4835 | 0.3840 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7462.095 | 1.0058 | 1.0302 | 0.3840 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7462.095 | 0.0077 | -1.0000 | 0.3840 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7463.094 | 0.9653 | 0.8939 | 0.6482 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.00253 | uM | 7463.094 | 0.7959 | 0.4063 | 0.6482 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7463.094 | 0.8053 | 0.4321 | 0.6482 |