Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | Imatinib | ABL/KIT/PDGFR | nRTK | 0.904 | uM | 7545.092 | 1.0417 | 1.0853 | 0.9794 | |
| T47DKBLUC | Unknown | Unknown | Imatinib | ABL/KIT/PDGFR | nRTK | 4.52 | uM | 7545.092 | 0.9631 | 0.9247 | 0.9794 | |
| T47DKBLUC | Unknown | Unknown | Imatinib | ABL/KIT/PDGFR | nRTK | 22.6 | uM | 7545.092 | 0.7317 | 0.4538 | 0.9794 | |
| T47DKBLUC | Unknown | Unknown | Imatinib | ABL/KIT/PDGFR | nRTK | 113 | uM | 7545.092 | 0.0145 | -0.9735 | 0.9794 | |
| T47DKBLUC | Unknown | Unknown | Imatinib | ABL/KIT/PDGFR | nRTK | 565 | uM | 7545.092 | 0.0080 | -0.9856 | 0.9794 | |
| T47DKBLUC | Unknown | Unknown | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00145 | uM | 7546.091 | 0.9928 | 0.9842 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00723 | uM | 7546.091 | 1.0403 | 1.0884 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | Imatinib | ABL/KIT/PDGFR | nRTK | 0.0362 | uM | 7546.091 | 0.9960 | 0.9913 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | Imatinib | ABL/KIT/PDGFR | nRTK | 0.181 | uM | 7546.091 | 0.9721 | 0.9389 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | Imatinib | ABL/KIT/PDGFR | nRTK | 0.904 | uM | 7546.091 | 1.0557 | 1.1223 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | Imatinib | ABL/KIT/PDGFR | nRTK | 4.52 | uM | 7546.091 | 0.9266 | 0.8400 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | Imatinib | ABL/KIT/PDGFR | nRTK | 22.6 | uM | 7546.091 | 0.6107 | 0.1657 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | Imatinib | ABL/KIT/PDGFR | nRTK | 113 | uM | 7546.091 | 0.0130 | -0.9827 | 0.9137 | |
| T47DKBLUC | Unknown | Unknown | Imatinib | ABL/KIT/PDGFR | nRTK | 565 | uM | 7546.091 | 0.0085 | -0.9892 | 0.9137 | |
| UACC-812 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00145 | uM | 7547.092 | 0.8569 | 0.7102 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00723 | uM | 7547.092 | 0.7912 | 0.5774 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.0362 | uM | 7547.092 | 0.8924 | 0.7820 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.181 | uM | 7547.092 | 0.9503 | 0.8992 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.904 | uM | 7547.092 | 0.9372 | 0.8728 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 4.52 | uM | 7547.092 | 0.7742 | 0.5430 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 22.6 | uM | 7547.092 | 0.5934 | 0.1784 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 113 | uM | 7547.092 | 0.0184 | -0.9651 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 565 | uM | 7547.092 | 0.0084 | -0.9843 | 0.9866 | |
| ZR-75-1 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00145 | uM | 7553.091 | 0.9715 | 0.9414 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00723 | uM | 7553.091 | 1.0394 | 1.0809 | 0.9738 |