Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | Ibandronate | FDPS | 0.0192 | uM | 11058.143 | 1.0284 | 1.0241 | 2.3374 | ||
| SUM229PE | TNBC | - | Ibandronate | FDPS | 0.096 | uM | 11058.143 | 0.9918 | 0.9930 | 2.3374 | ||
| SUM229PE | TNBC | - | Ibandronate | FDPS | 0.48 | uM | 11058.143 | 0.9980 | 0.9983 | 2.3374 | ||
| SUM229PE | TNBC | - | Ibandronate | FDPS | 2.4 | uM | 11058.143 | 0.9574 | 0.9631 | 2.3374 | ||
| SUM229PE | TNBC | - | Ibandronate | FDPS | 12 | uM | 11058.143 | 0.8803 | 0.8938 | 2.3374 | ||
| SUM229PE | TNBC | - | Ibandronate | FDPS | 60 | uM | 11058.143 | 0.5416 | 0.5385 | 2.3374 | ||
| SUM229PE | TNBC | - | Ibandronate | FDPS | 300 | uM | 11058.143 | 0.3438 | 0.2666 | 2.3374 | ||
| SUM229PE | TNBC | - | Ibandronate | FDPS | 1500 | uM | 11058.143 | 0.2336 | 0.0736 | 2.3374 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10695.143 | 1.0289 | 1.0448 | 1.2894 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10695.143 | 0.9502 | 0.9224 | 1.2894 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 10695.143 | 0.9499 | 0.9219 | 1.2894 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 10695.143 | 1.0236 | 1.0365 | 1.2894 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 10695.143 | 1.0605 | 1.0932 | 1.2894 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 10695.143 | 0.9205 | 0.8755 | 1.2894 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 10695.143 | 0.6123 | 0.3671 | 1.2894 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 10695.143 | 0.3487 | -0.1165 | 1.2894 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 10695.143 | 0.2814 | -0.2519 | 1.2894 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 11852.143 | 1.0699 | 1.1130 | 1.2284 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 11852.143 | 0.9792 | 0.9661 | 1.2284 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 11852.143 | 1.0387 | 1.0627 | 1.2284 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 11852.143 | 1.0899 | 1.1452 | 1.2284 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 11852.143 | 1.0826 | 1.1335 | 1.2284 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 11852.143 | 0.8272 | 0.7139 | 1.2284 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 11852.143 | 0.5279 | 0.1890 | 1.2284 | ||
| SUM52PE | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 11852.143 | 0.4168 | -0.0191 | 1.2284 |