Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 0.00384 | uM | 12056.143 | 0.9998 | 0.9996 | 1.0075 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 0.0192 | uM | 12056.143 | 0.9522 | 0.9051 | 1.0075 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 0.096 | uM | 12056.143 | 0.9772 | 0.9546 | 1.0075 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 0.48 | uM | 12056.143 | 0.9597 | 0.9200 | 1.0075 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 2.4 | uM | 12056.143 | 0.9838 | 0.9678 | 1.0075 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 12 | uM | 12056.143 | 0.9674 | 0.9353 | 1.0075 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 60 | uM | 12056.143 | 0.8584 | 0.7187 | 1.0075 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 300 | uM | 12056.143 | 0.5836 | 0.1718 | 1.0075 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 1500 | uM | 12056.143 | 0.5291 | 0.0633 | 1.0075 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 0.00384 | uM | 12178.143 | 0.9986 | 0.9962 | 0.7617 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 0.0192 | uM | 12178.143 | 1.0095 | 1.0250 | 0.7617 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 0.096 | uM | 12178.143 | 0.9881 | 0.9688 | 0.7617 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 0.48 | uM | 12178.143 | 0.9717 | 0.9260 | 0.7617 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 2.4 | uM | 12178.143 | 1.0571 | 1.1513 | 0.7617 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 12 | uM | 12178.143 | 0.9591 | 0.8933 | 0.7617 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 60 | uM | 12178.143 | 0.8911 | 0.7190 | 0.7617 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 300 | uM | 12178.143 | 0.5952 | 0.0121 | 0.7617 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 1500 | uM | 12178.143 | 0.5671 | -0.0502 | 0.7617 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 0.00384 | uM | 12291.143 | 1.0267 | 1.0961 | 0.5621 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 0.0192 | uM | 12291.143 | 0.9997 | 0.9988 | 0.5621 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 0.096 | uM | 12291.143 | 1.0237 | 1.0852 | 0.5621 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 0.48 | uM | 12291.143 | 1.0113 | 1.0403 | 0.5621 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 2.4 | uM | 12291.143 | 0.8992 | 0.6556 | 0.5621 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 12 | uM | 12291.143 | 1.0756 | 1.2767 | 0.5621 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 60 | uM | 12291.143 | 0.8111 | 0.3779 | 0.5621 |