Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 113 | uM | 7489.09 | 0.0115 | -0.7907 | 1.9790 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 565 | uM | 7489.09 | 0.0053 | -0.8584 | 1.9790 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00145 | uM | 7490.091 | 0.9353 | 0.9484 | 2.5547 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00723 | uM | 7490.091 | 0.9611 | 0.9692 | 2.5547 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.0362 | uM | 7490.091 | 0.9448 | 0.9560 | 2.5547 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.181 | uM | 7490.091 | 0.9550 | 0.9643 | 2.5547 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.904 | uM | 7490.091 | 0.9742 | 0.9797 | 2.5547 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 4.52 | uM | 7490.091 | 0.9976 | 0.9981 | 2.5547 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 22.6 | uM | 7490.091 | 0.8965 | 0.9163 | 2.5547 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 113 | uM | 7490.091 | 0.0914 | -0.2161 | 2.5547 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 565 | uM | 7490.091 | 0.0079 | -0.6995 | 2.5547 | |
| MCF7 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00145 | uM | 7492.091 | 0.9783 | 0.9701 | 1.4539 | |
| MCF7 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00723 | uM | 7492.091 | 1.1090 | 1.1474 | 1.4539 | |
| MCF7 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.0362 | uM | 7492.091 | 0.9728 | 0.9625 | 1.4539 | |
| MCF7 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.181 | uM | 7492.091 | 0.9549 | 0.9375 | 1.4539 | |
| MCF7 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.904 | uM | 7492.091 | 0.9780 | 0.9697 | 1.4539 | |
| MCF7 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 4.52 | uM | 7492.091 | 0.8663 | 0.8120 | 1.4539 | |
| MCF7 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 22.6 | uM | 7492.091 | 0.6476 | 0.4834 | 1.4539 | |
| MCF7 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 113 | uM | 7492.091 | 0.0134 | -0.8970 | 1.4539 | |
| MCF7 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 565 | uM | 7492.091 | 0.0046 | -0.9505 | 1.4539 | |
| MCF7 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00145 | uM | 7493.091 | 1.0188 | 1.0347 | 1.0859 | |
| MCF7 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00723 | uM | 7493.091 | 0.9913 | 0.9839 | 1.0859 | |
| MCF7 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.0362 | uM | 7493.091 | 1.0029 | 1.0054 | 1.0859 | |
| MCF7 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.181 | uM | 7493.091 | 1.0322 | 1.0592 | 1.0859 | |
| MCF7 | HR+ | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.904 | uM | 7493.091 | 0.9902 | 0.9820 | 1.0859 |