Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMT-3522 S1 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 6.67 | uM | 7911.001 | 0.0716 | -0.7777 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 33.3 | uM | 7911.001 | 0.0088 | -0.9614 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 10124.001 | 1.2236 | 1.1934 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.000427 | uM | 10124.001 | 0.9431 | 0.9471 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.00213 | uM | 10124.001 | 0.8604 | 0.8671 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.0107 | uM | 10124.001 | 0.8556 | 0.8623 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.0533 | uM | 10124.001 | 0.3285 | 0.2018 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.267 | uM | 10124.001 | 0.4063 | 0.3246 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 1.33 | uM | 10124.001 | 0.6121 | 0.5978 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 6.67 | uM | 10124.001 | 0.2318 | 0.0248 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 33.3 | uM | 10124.001 | 0.0021 | -0.8812 | 2.1861 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 10147.001 | 0.9403 | 0.9520 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.000427 | uM | 10147.001 | 1.0114 | 1.0089 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.00213 | uM | 10147.001 | 0.9355 | 0.9480 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.0107 | uM | 10147.001 | 0.6787 | 0.7161 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.0533 | uM | 10147.001 | 0.1137 | -0.1527 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 0.267 | uM | 10147.001 | 0.2390 | 0.1363 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 1.33 | uM | 10147.001 | 0.3259 | 0.2843 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 6.67 | uM | 10147.001 | 0.1230 | -0.1261 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK461364 | PLK1 | PLK | 33.3 | uM | 10147.001 | 0.0042 | -0.7694 | 2.5313 | |
| Hs 578T | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 7863.001 | 1.0188 | 1.0214 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7863.001 | 1.0119 | 1.0135 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7863.001 | 0.7224 | 0.6616 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7863.001 | 0.3326 | 0.0678 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7863.001 | 0.3075 | 0.0209 | 1.7540 |