Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 9294.017 | 0.1963 | -0.7281 | 0.8160 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7824.017 | 0.9401 | 0.9274 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7824.017 | 0.9984 | 0.9981 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7824.017 | 0.9053 | 0.8842 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7824.017 | 0.9359 | 0.9221 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7824.017 | 0.7850 | 0.7301 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7824.017 | 0.6601 | 0.5594 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7824.017 | 0.4766 | 0.2831 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7824.017 | 0.2738 | -0.0794 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7824.017 | 0.1504 | -0.3571 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7825.017 | 0.9337 | 0.9353 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7825.017 | 1.0222 | 1.0212 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7825.017 | 0.8651 | 0.8657 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7825.017 | 0.7725 | 0.7671 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7825.017 | 0.5988 | 0.5641 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7825.017 | 0.4635 | 0.3832 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7825.017 | 0.3027 | 0.1277 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7825.017 | 0.2012 | -0.0729 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7825.017 | 0.1170 | -0.2852 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 9347.017 | 1.0439 | 1.0536 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 9347.017 | 1.0634 | 1.0771 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 9347.017 | 0.9798 | 0.9750 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 9347.017 | 0.9178 | 0.8972 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 9347.017 | 0.7216 | 0.6362 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 9347.017 | 0.6621 | 0.5517 | 1.6249 |