Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7531.098 | 1.0632 | 1.0356 | 3.4793 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7531.098 | 0.5503 | 0.6845 | 3.4793 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7531.098 | 0.5168 | 0.6543 | 3.4793 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7531.098 | 0.2141 | 0.2842 | 3.4793 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7532.071 | 0.9726 | 0.9332 | 0.8178 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7532.071 | 0.9872 | 0.9688 | 0.8178 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7532.071 | 0.9479 | 0.8733 | 0.8178 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7532.071 | 0.9355 | 0.8434 | 0.8178 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7532.071 | 0.8961 | 0.7489 | 0.8178 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7532.071 | 0.8269 | 0.5853 | 0.8178 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7532.071 | 0.8480 | 0.6349 | 0.8178 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 24 | uM | 7532.071 | 0.0133 | -0.9898 | 0.8178 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 120 | uM | 7532.071 | 0.0078 | -0.9947 | 0.8178 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7532.091 | 1.0127 | 1.0270 | 0.9414 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7532.091 | 1.0816 | 1.1739 | 0.9414 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7532.091 | 1.0060 | 1.0128 | 0.9414 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7532.091 | 1.0837 | 1.1783 | 0.9414 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7532.091 | 1.0240 | 1.0510 | 0.9414 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7532.091 | 0.8702 | 0.7255 | 0.9414 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7532.091 | 0.6737 | 0.3147 | 0.9414 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7532.091 | 0.8119 | 0.6030 | 0.9414 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7532.091 | 0.0093 | -0.9860 | 0.9414 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7532.098 | 1.0508 | 1.1469 | 0.6992 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7532.098 | 0.9137 | 0.7579 | 0.6992 | |
| SUM185PE | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7532.098 | 0.9931 | 0.9802 | 0.6992 |