Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 9044.091 | 1.0158 | 1.0492 | 0.6432 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 9044.091 | 1.0102 | 1.0317 | 0.6432 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 9044.091 | 1.0160 | 1.0499 | 0.6432 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 9044.091 | 1.0181 | 1.0565 | 0.6432 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 9044.091 | 0.9127 | 0.7353 | 0.6432 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 9044.091 | 0.8511 | 0.5566 | 0.6432 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 9044.091 | 0.8504 | 0.5547 | 0.6432 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 9044.091 | 0.8442 | 0.5371 | 0.6432 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 9044.091 | 0.8458 | 0.5416 | 0.6432 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 9044.098 | 0.9849 | 0.9656 | 0.8807 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 9044.098 | 1.0174 | 1.0396 | 0.8807 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 9044.098 | 0.9586 | 0.9063 | 0.8807 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 9044.098 | 1.0047 | 1.0107 | 0.8807 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 9044.098 | 0.9508 | 0.8886 | 0.8807 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 9044.098 | 0.8281 | 0.6144 | 0.8807 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 9044.098 | 0.8041 | 0.5615 | 0.8807 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 9044.098 | 0.2700 | -0.5477 | 0.8807 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 9044.098 | 0.8226 | 0.6023 | 0.8807 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 10381.092 | 1.0026 | 1.0037 | 1.4137 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 10381.092 | 0.9758 | 0.9656 | 1.4137 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 10381.092 | 0.9191 | 0.8842 | 1.4137 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 10381.092 | 0.9769 | 0.9673 | 1.4137 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 10381.092 | 0.9250 | 0.8926 | 1.4137 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 10381.092 | 0.7908 | 0.6941 | 1.4137 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 10381.092 | 0.7962 | 0.7022 | 1.4137 |