Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 6.67 | uM | 10124.001 | 0.1973 | -0.0481 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 33.3 | uM | 10124.001 | 0.0138 | -0.7178 | 2.1861 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.0000853 | uM | 10147.001 | 0.9941 | 0.9953 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.000427 | uM | 10147.001 | 1.0546 | 1.0425 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.00213 | uM | 10147.001 | 0.9937 | 0.9950 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.0107 | uM | 10147.001 | 0.8204 | 0.8495 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.0533 | uM | 10147.001 | 0.5598 | 0.5904 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.267 | uM | 10147.001 | 0.5714 | 0.6033 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK1070916 | AURK | AURK | 1.33 | uM | 10147.001 | 0.5785 | 0.6111 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK1070916 | AURK | AURK | 6.67 | uM | 10147.001 | 0.1422 | -0.0744 | 2.5313 | |
| HMT-3522 T4-2 | Unknown | Unknown | GSK1070916 | AURK | AURK | 33.3 | uM | 10147.001 | 0.0028 | -0.8035 | 2.5313 | |
| Hs 578T | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7863.001 | 0.9585 | 0.9523 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.000427 | uM | 7863.001 | 1.0312 | 1.0353 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.00213 | uM | 7863.001 | 1.0087 | 1.0099 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 7863.001 | 0.7813 | 0.7375 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 7863.001 | 0.7278 | 0.6686 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.267 | uM | 7863.001 | 0.7182 | 0.6561 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK1070916 | AURK | AURK | 1.33 | uM | 7863.001 | 0.5947 | 0.4871 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK1070916 | AURK | AURK | 6.67 | uM | 7863.001 | 0.3135 | 0.0323 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK1070916 | AURK | AURK | 33.3 | uM | 7863.001 | 0.0078 | -0.8746 | 1.7540 | |
| Hs 578T | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7864.001 | 0.8741 | 0.8281 | 1.4976 | |
| Hs 578T | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.000427 | uM | 7864.001 | 0.9717 | 0.9621 | 1.4976 | |
| Hs 578T | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.00213 | uM | 7864.001 | 0.9832 | 0.9774 | 1.4976 | |
| Hs 578T | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 7864.001 | 0.8547 | 0.8009 | 1.4976 | |
| Hs 578T | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 7864.001 | 0.7568 | 0.6604 | 1.4976 |