Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12608.169 | 0.9289 | 0.8859 | 1.2559 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10580.138 | 0.9585 | 0.9135 | 0.9584 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10580.138 | 0.9547 | 0.9056 | 0.9584 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10580.138 | 0.9205 | 0.8344 | 0.9584 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10580.138 | 0.9413 | 0.8777 | 0.9584 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10580.138 | 0.9300 | 0.8541 | 0.9584 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10580.138 | 0.9800 | 0.9583 | 0.9584 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10580.138 | 0.8313 | 0.6493 | 0.9584 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10580.138 | 0.8175 | 0.6208 | 0.9584 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10580.138 | 0.7546 | 0.4908 | 0.9584 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10754.15 | 0.9816 | 0.9683 | 1.1628 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10754.15 | 0.9583 | 0.9281 | 1.1628 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10754.15 | 1.0233 | 1.0400 | 1.1628 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10754.15 | 0.9229 | 0.8666 | 1.1628 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10754.15 | 1.0369 | 1.0632 | 1.1628 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10754.15 | 0.9855 | 0.9750 | 1.1628 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10754.15 | 0.7881 | 0.6296 | 1.1628 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10754.15 | 0.7939 | 0.6399 | 1.1628 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10754.15 | 0.6305 | 0.3450 | 1.1628 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 11938.16 | 0.9841 | 0.9507 | 0.6405 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 11938.16 | 0.9300 | 0.7858 | 0.6405 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 11938.16 | 0.9202 | 0.7565 | 0.6405 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 11938.16 | 0.9449 | 0.8307 | 0.6405 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 11938.16 | 0.9240 | 0.7677 | 0.6405 | ||
| UACC-812 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 11938.16 | 1.0127 | 1.0399 | 0.6405 |