Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9294.019 | 0.9805 | 0.9549 | 0.8608 | |
| HCC1428 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9294.019 | 0.9554 | 0.8966 | 0.8608 | |
| HCC1428 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9294.019 | 0.9318 | 0.8424 | 0.8608 | |
| HCC1428 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9294.019 | 0.9529 | 0.8909 | 0.8608 | |
| HCC1428 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9294.019 | 0.8862 | 0.7381 | 0.8608 | |
| HCC1428 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9294.019 | 0.1100 | -0.8460 | 0.8608 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7824.016 | 0.9559 | 0.9481 | 1.7164 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7824.016 | 0.9652 | 0.9591 | 1.7164 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7824.016 | 0.9313 | 0.9188 | 1.7164 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7824.016 | 1.0204 | 1.0237 | 1.7164 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7824.016 | 0.9934 | 0.9923 | 1.7164 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 7824.016 | 0.9660 | 0.9601 | 1.7164 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 7824.016 | 0.9074 | 0.8900 | 1.7164 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 7824.016 | 0.6117 | 0.5020 | 1.7164 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 7824.016 | 0.1025 | -0.4694 | 1.7164 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7825.016 | 0.9594 | 0.9507 | 1.6601 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7825.016 | 0.9880 | 0.9855 | 1.6601 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7825.016 | 1.0306 | 1.0366 | 1.6601 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7825.016 | 0.9502 | 0.9393 | 1.6601 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7825.016 | 0.9982 | 0.9979 | 1.6601 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 7825.016 | 0.9029 | 0.8807 | 1.6601 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 7825.016 | 0.8314 | 0.7895 | 1.6601 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 7825.016 | 0.6212 | 0.5014 | 1.6601 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 7825.016 | 0.3407 | 0.0456 | 1.6601 | |
| HCC1569 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7827.016 | 0.9431 | 0.9231 | 1.4950 |