Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7818.016 | 0.6340 | 0.2152 | 0.9146 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7818.016 | 0.2182 | -0.6214 | 0.9146 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7819.016 | 0.9938 | 0.9769 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7819.016 | 1.0696 | 1.2691 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7819.016 | 0.9960 | 0.9850 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7819.016 | 1.0533 | 1.2047 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7819.016 | 0.9986 | 0.9947 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7819.016 | 1.0348 | 1.1325 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7819.016 | 0.8570 | 0.4973 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7819.016 | 0.6777 | -0.0360 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7819.016 | 0.2137 | -0.8894 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7820.016 | 1.0232 | 1.1056 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7820.016 | 0.9676 | 0.8576 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7820.016 | 1.0083 | 1.0375 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7820.016 | 0.9452 | 0.7631 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7820.016 | 0.9522 | 0.7922 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7820.016 | 0.8752 | 0.4838 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7820.016 | 0.9672 | 0.8560 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7820.016 | 0.7122 | -0.0647 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7820.016 | 0.2297 | -0.9258 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7821.016 | 1.0330 | 1.2207 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7821.016 | 1.0249 | 1.1653 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7821.016 | 1.0981 | 1.7044 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7821.016 | 0.9999 | 0.9994 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7821.016 | 1.0161 | 1.1057 | 0.3100 |