Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7506.085 | 0.9862 | 0.9749 | 1.0985 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7506.085 | 0.9879 | 0.9780 | 1.0985 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7506.085 | 0.9994 | 0.9988 | 1.0985 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7506.085 | 0.8947 | 0.8073 | 1.0985 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7506.085 | 0.0168 | -0.9516 | 1.0985 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7506.085 | 0.0139 | -0.9592 | 1.0985 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7506.085 | 0.0133 | -0.9609 | 1.0985 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7506.085 | 0.0066 | -0.9793 | 1.0985 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7507.084 | 1.0071 | 1.0127 | 1.1207 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7507.084 | 0.9387 | 0.8902 | 1.1207 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7507.084 | 1.0065 | 1.0115 | 1.1207 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7507.084 | 0.9742 | 0.9538 | 1.1207 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7507.084 | 0.9257 | 0.8669 | 1.1207 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7507.084 | 0.0087 | -0.9711 | 1.1207 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7507.084 | 0.0058 | -0.9797 | 1.1207 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7507.084 | 0.0085 | -0.9716 | 1.1207 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7507.084 | 0.0068 | -0.9768 | 1.1207 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7508.084 | 1.0427 | 1.1107 | 0.7756 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7508.084 | 1.0001 | 1.0003 | 0.7756 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7508.084 | 0.9790 | 0.9461 | 0.7756 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7508.084 | 1.0083 | 1.0214 | 0.7756 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7508.084 | 0.8909 | 0.7232 | 0.7756 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7508.084 | 0.0086 | -0.9956 | 0.7756 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7508.084 | 0.0071 | -0.9966 | 0.7756 | |
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7508.084 | 0.0131 | -0.9925 | 0.7756 |