Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 7447.074 | 0.9554 | 0.9416 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 7447.074 | 0.9693 | 0.9600 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 7447.074 | 0.9312 | 0.9095 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 7447.074 | 0.8361 | 0.7807 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 7447.074 | 0.7448 | 0.6519 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 66.7 | uM | 7447.074 | 0.5278 | 0.3212 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 333 | uM | 7447.074 | 0.4274 | 0.1521 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 7448.074 | 1.0067 | 1.0047 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 7448.074 | 0.9729 | 0.9810 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 7448.074 | 0.9702 | 0.9791 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 7448.074 | 0.9587 | 0.9710 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 7448.074 | 0.9578 | 0.9703 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 7448.074 | 0.8605 | 0.8984 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 7448.074 | 0.8377 | 0.8809 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 66.7 | uM | 7448.074 | 0.5787 | 0.6544 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 333 | uM | 7448.074 | 0.3347 | 0.3682 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 7449.074 | 1.0279 | 1.0273 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 7449.074 | 1.0282 | 1.0276 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 7449.074 | 1.0168 | 1.0165 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 7449.074 | 1.0058 | 1.0057 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 7449.074 | 1.0244 | 1.0238 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 7449.074 | 0.8848 | 0.8831 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 7449.074 | 0.8151 | 0.8086 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 66.7 | uM | 7449.074 | 0.6298 | 0.5931 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 333 | uM | 7449.074 | 0.3112 | 0.1261 | 2.0321 |