Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.000256 | uM | 11937.161 | 0.8939 | 0.9106 | 2.4516 | |
| SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.00128 | uM | 11937.161 | 0.9364 | 0.9471 | 2.4516 | |
| SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0064 | uM | 11937.161 | 0.9152 | 0.9290 | 2.4516 | |
| SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.032 | uM | 11937.161 | 0.8474 | 0.8693 | 2.4516 | |
| SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.16 | uM | 11937.161 | 0.9079 | 0.9227 | 2.4516 | |
| SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.8 | uM | 11937.161 | 0.8356 | 0.8587 | 2.4516 | |
| SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 4 | uM | 11937.161 | 0.8478 | 0.8697 | 2.4516 | |
| SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 20 | uM | 11937.161 | 0.5813 | 0.6030 | 2.4516 | |
| SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 100 | uM | 11937.161 | 0.1940 | 0.0245 | 2.4516 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0000853 | uM | 10520.137 | 0.8662 | 0.9255 | 3.7823 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.000427 | uM | 10520.137 | 0.8907 | 0.9397 | 3.7823 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.00213 | uM | 10520.137 | 1.0290 | 1.0152 | 3.7823 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0107 | uM | 10520.137 | 1.0977 | 1.0499 | 3.7823 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0533 | uM | 10520.137 | 0.7912 | 0.8799 | 3.7823 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.267 | uM | 10520.137 | 0.7812 | 0.8736 | 3.7823 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 1.33 | uM | 10520.137 | 0.8138 | 0.8940 | 3.7823 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 6.67 | uM | 10520.137 | 0.8812 | 0.9343 | 3.7823 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 33.3 | uM | 10520.137 | 0.7122 | 0.8283 | 3.7823 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0000853 | uM | 11057.149 | 0.9239 | 0.9618 | 4.1019 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.000427 | uM | 11057.149 | 1.0080 | 1.0039 | 4.1019 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.00213 | uM | 11057.149 | 0.9177 | 0.9586 | 4.1019 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0107 | uM | 11057.149 | 0.9100 | 0.9545 | 4.1019 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0533 | uM | 11057.149 | 0.9025 | 0.9506 | 4.1019 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.267 | uM | 11057.149 | 0.9288 | 0.9643 | 4.1019 | |
| SUM159PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 1.33 | uM | 11057.149 | 1.0274 | 1.0132 | 4.1019 |