Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 5908.074 | 0.8474 | 0.4567 | 0.5224 | |
| BT-483 | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 5908.074 | 0.8114 | 0.3407 | 0.5224 | |
| BT-483 | HR+ | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 5908.074 | 0.7089 | 0.0350 | 0.5224 | |
| BT-483 | HR+ | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 5908.074 | 0.6526 | -0.1166 | 0.5224 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 5909.074 | 1.1063 | 1.0719 | 2.8598 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 5909.074 | 1.0216 | 1.0150 | 2.8598 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 5909.074 | 1.0639 | 1.0438 | 2.8598 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 5909.074 | 1.1036 | 1.0702 | 2.8598 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 5909.074 | 0.7739 | 0.8285 | 2.8598 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 5909.074 | 0.4687 | 0.5344 | 2.8598 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 5909.074 | 0.1301 | -0.0199 | 2.8598 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 5909.074 | 0.0299 | -0.4136 | 2.8598 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 5909.074 | 0.0073 | -0.6414 | 2.8598 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 5910.074 | 1.0230 | 1.0142 | 3.2172 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 5910.074 | 1.0233 | 1.0144 | 3.2172 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 5910.074 | 0.9507 | 0.9688 | 3.2172 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 5910.074 | 0.9943 | 0.9965 | 3.2172 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 5910.074 | 0.5825 | 0.6908 | 3.2172 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 5910.074 | 0.3090 | 0.3884 | 3.2172 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 5910.074 | 0.0548 | -0.1890 | 3.2172 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 5910.074 | 0.0187 | -0.4191 | 3.2172 | |
| BT-549 | TNBC | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 5910.074 | 0.0005 | -0.8162 | 3.2172 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 5911.074 | 0.9171 | 0.8528 | 1.1317 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 5911.074 | 0.8927 | 0.8091 | 1.1317 | |
| CAMA-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 5911.074 | 0.9243 | 0.8656 | 1.1317 |