Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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BT-474 | HER2amp | Luminal | 2-deoxyglucose | 3330 | uM | 13125.177 | 0.4602 | -0.1564 | 0.8991 | |||
CAMA-1 | HR+ | Luminal | 2-deoxyglucose | 0.00853 | uM | 12647.177 | 0.9710 | 0.9442 | 1.0387 | |||
CAMA-1 | HR+ | Luminal | 2-deoxyglucose | 0.0427 | uM | 12647.177 | 0.9361 | 0.8768 | 1.0387 | |||
CAMA-1 | HR+ | Luminal | 2-deoxyglucose | 0.213 | uM | 12647.177 | 0.9432 | 0.8905 | 1.0387 | |||
CAMA-1 | HR+ | Luminal | 2-deoxyglucose | 1.07 | uM | 12647.177 | 0.9167 | 0.8393 | 1.0387 | |||
CAMA-1 | HR+ | Luminal | 2-deoxyglucose | 5.33 | uM | 12647.177 | 0.9777 | 0.9570 | 1.0387 | |||
CAMA-1 | HR+ | Luminal | 2-deoxyglucose | 26.7 | uM | 12647.177 | 0.9551 | 0.9134 | 1.0387 | |||
CAMA-1 | HR+ | Luminal | 2-deoxyglucose | 133 | uM | 12647.177 | 0.9520 | 0.9075 | 1.0387 | |||
CAMA-1 | HR+ | Luminal | 2-deoxyglucose | 667 | uM | 12647.177 | 0.8865 | 0.7809 | 1.0387 | |||
CAMA-1 | HR+ | Luminal | 2-deoxyglucose | 3330 | uM | 12647.177 | 0.7539 | 0.5238 | 1.0387 | |||
HCC1143 | TNBC | Basal A | 2-deoxyglucose | 0.00853 | uM | 13099.177 | 0.8332 | 0.5639 | 0.7419 | |||
HCC1143 | TNBC | Basal A | 2-deoxyglucose | 0.0427 | uM | 13099.177 | 1.3958 | 2.1350 | 0.7419 | |||
HCC1143 | TNBC | Basal A | 2-deoxyglucose | 0.213 | uM | 13099.177 | 1.1952 | 1.5434 | 0.7419 | |||
HCC1143 | TNBC | Basal A | 2-deoxyglucose | 1.07 | uM | 13099.177 | 1.1578 | 1.4366 | 0.7419 | |||
HCC1143 | TNBC | Basal A | 2-deoxyglucose | 5.33 | uM | 13099.177 | 1.1548 | 1.4280 | 0.7419 | |||
HCC1143 | TNBC | Basal A | 2-deoxyglucose | 26.7 | uM | 13099.177 | 0.9038 | 0.7451 | 0.7419 | |||
HCC1143 | TNBC | Basal A | 2-deoxyglucose | 133 | uM | 13099.177 | 1.0659 | 1.1795 | 0.7419 | |||
HCC1143 | TNBC | Basal A | 2-deoxyglucose | 667 | uM | 13099.177 | 1.1517 | 1.4195 | 0.7419 | |||
HCC1143 | TNBC | Basal A | 2-deoxyglucose | 3330 | uM | 13099.177 | 0.5883 | -0.0218 | 0.7419 | |||
HCC1419 | HER2amp | Luminal | 2-deoxyglucose | 0.00853 | uM | 12612.177 | 0.9327 | 0.7455 | 0.5119 | |||
HCC1419 | HER2amp | Luminal | 2-deoxyglucose | 0.0427 | uM | 12612.177 | 0.9475 | 0.7999 | 0.5119 | |||
HCC1419 | HER2amp | Luminal | 2-deoxyglucose | 0.213 | uM | 12612.177 | 0.9231 | 0.7105 | 0.5119 | |||
HCC1419 | HER2amp | Luminal | 2-deoxyglucose | 1.07 | uM | 12612.177 | 0.9413 | 0.7770 | 0.5119 | |||
HCC1419 | HER2amp | Luminal | 2-deoxyglucose | 5.33 | uM | 12612.177 | 0.9238 | 0.7130 | 0.5119 | |||
HCC1419 | HER2amp | Luminal | 2-deoxyglucose | 26.7 | uM | 12612.177 | 0.9224 | 0.7081 | 0.5119 |