Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7821.007 | 0.5817 | -0.0944 | 0.6838 | |
| HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7821.007 | 0.2462 | -0.7425 | 0.6838 | |
| HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7821.007 | 0.1854 | -0.8299 | 0.6838 | |
| HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7821.007 | 0.7269 | 0.2544 | 0.6838 | |
| HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 9278.121 | 1.0603 | 1.2782 | 0.4498 | |
| HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 9278.121 | 1.0011 | 1.0050 | 0.4498 | |
| HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 9278.121 | 1.0501 | 1.2295 | 0.4498 | |
| HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0294 | uM | 9278.121 | 1.0074 | 1.0328 | 0.4498 | |
| HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.147 | uM | 9278.121 | 0.9699 | 0.8688 | 0.4498 | |
| HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.736 | uM | 9278.121 | 0.7856 | 0.1697 | 0.4498 | |
| HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 3.68 | uM | 9278.121 | 0.3003 | -0.8621 | 0.4498 | |
| HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 18.4 | uM | 9278.121 | 0.2586 | -0.9011 | 0.4498 | |
| HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 92 | uM | 9278.121 | 0.0082 | -1.0000 | 0.4498 | |
| HCC1428 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 9294.121 | 1.0415 | 1.1113 | 0.7502 | |
| HCC1428 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 9294.121 | 1.0222 | 1.0594 | 0.7502 | |
| HCC1428 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 9294.121 | 0.9981 | 0.9948 | 0.7502 | |
| HCC1428 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0294 | uM | 9294.121 | 1.0347 | 1.0932 | 0.7502 | |
| HCC1428 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.147 | uM | 9294.121 | 1.0495 | 1.1330 | 0.7502 | |
| HCC1428 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.736 | uM | 9294.121 | 1.0996 | 1.2700 | 0.7502 | |
| HCC1428 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 3.68 | uM | 9294.121 | 0.0878 | -0.9218 | 0.7502 | |
| HCC1428 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 18.4 | uM | 9294.121 | 0.0618 | -0.9511 | 0.7502 | |
| HCC1428 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 92 | uM | 9294.121 | 0.0249 | -0.9855 | 0.7502 | |
| HCC1428 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 9299.121 | 1.0843 | 1.4333 | 0.4126 | |
| HCC1428 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 9299.121 | 0.9921 | 0.9617 | 0.4126 | |
| HCC1428 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 9299.121 | 1.0788 | 1.4035 | 0.4126 |