Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9972.002 | 0.6586 | 0.3202 | 1.0054 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9972.002 | 0.6176 | 0.2383 | 1.0054 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9997.002 | 0.9960 | 0.9918 | 0.9751 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9997.002 | 1.0596 | 1.1224 | 0.9751 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9997.002 | 1.0196 | 1.0402 | 0.9751 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9997.002 | 0.9886 | 0.9765 | 0.9751 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9997.002 | 0.8289 | 0.6499 | 0.9751 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9997.002 | 0.7471 | 0.4832 | 0.9751 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9997.002 | 0.7170 | 0.4219 | 0.9751 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9997.002 | 0.7322 | 0.4528 | 0.9751 | |
| ZR75B | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9997.002 | 0.7077 | 0.4029 | 0.9751 | |
| 184A1 | NM | Basal | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 9047.121 | 1.0627 | 1.1591 | 0.7949 | |
| 184A1 | NM | Basal | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 9047.121 | 0.8885 | 0.7236 | 0.7949 | |
| 184A1 | NM | Basal | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 9047.121 | 0.9506 | 0.8765 | 0.7949 | |
| 184A1 | NM | Basal | Doxorubicin | TOP2 | TOP | 0.0294 | uM | 9047.121 | 0.9625 | 0.9062 | 0.7949 | |
| 184A1 | NM | Basal | Doxorubicin | TOP2 | TOP | 0.147 | uM | 9047.121 | 0.7930 | 0.4938 | 0.7949 | |
| 184A1 | NM | Basal | Doxorubicin | TOP2 | TOP | 0.736 | uM | 9047.121 | 0.2446 | -0.6597 | 0.7949 | |
| 184A1 | NM | Basal | Doxorubicin | TOP2 | TOP | 3.68 | uM | 9047.121 | 0.1828 | -0.7641 | 0.7949 | |
| 184A1 | NM | Basal | Doxorubicin | TOP2 | TOP | 18.4 | uM | 9047.121 | 0.0340 | -0.9716 | 0.7949 | |
| 184A1 | NM | Basal | Doxorubicin | TOP2 | TOP | 92 | uM | 9047.121 | 0.0029 | -0.9987 | 0.7949 | |
| 184A1 | NM | Basal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 10002.034 | 0.9686 | 0.9075 | 0.6736 | |
| 184A1 | NM | Basal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 10002.034 | 0.9843 | 0.9534 | 0.6736 | |
| 184A1 | NM | Basal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 10002.034 | 0.9692 | 0.9093 | 0.6736 | |
| 184A1 | NM | Basal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 10002.034 | 0.9390 | 0.8216 | 0.6736 | |
| 184A1 | NM | Basal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 10002.034 | 0.7750 | 0.3699 | 0.6736 |