Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 12999.002 | 0.9689 | 0.9300 | 0.8869 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 12999.002 | 1.0425 | 1.0961 | 0.8869 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 12999.002 | 0.9737 | 0.9409 | 0.8869 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 12999.002 | 1.0335 | 1.0757 | 0.8869 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 12999.002 | 0.5614 | 0.0431 | 0.8869 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 12999.002 | 0.2590 | -0.5640 | 0.8869 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 12999.002 | 0.2466 | -0.5874 | 0.8869 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 12999.002 | 0.2617 | -0.5588 | 0.8869 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 12999.002 | 0.2802 | -0.5235 | 0.8869 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9797.002 | 0.9966 | 0.9833 | 0.4052 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9797.002 | 0.9882 | 0.9424 | 0.4052 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9797.002 | 0.8959 | 0.5246 | 0.4052 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9797.002 | 0.7132 | -0.1315 | 0.4052 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 9797.002 | 0.4161 | -0.7703 | 0.4052 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 9797.002 | 0.2603 | -0.9278 | 0.4052 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 9797.002 | 0.1968 | -0.9638 | 0.4052 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 9797.002 | 0.1763 | -0.9724 | 0.4052 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 9797.002 | 0.1797 | -0.9711 | 0.4052 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10139.002 | 1.0209 | 1.0481 | 0.8715 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10139.002 | 0.9926 | 0.9830 | 0.8715 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10139.002 | 0.9947 | 0.9879 | 0.8715 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10139.002 | 0.8313 | 0.6180 | 0.8715 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 10139.002 | 0.5350 | -0.0242 | 0.8715 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 10139.002 | 0.3213 | -0.4565 | 0.8715 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 10139.002 | 0.2923 | -0.5124 | 0.8715 |