Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9759.002 | 0.9489 | 0.9096 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9759.002 | 0.9293 | 0.8747 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9759.002 | 0.4186 | -0.0723 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9759.002 | 0.1375 | -0.6526 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9759.002 | 0.1354 | -0.6573 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9759.002 | 0.1152 | -0.7027 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9759.002 | 0.1716 | -0.5775 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9760.002 | 1.0647 | 1.1307 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9760.002 | 0.9650 | 0.9294 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9760.002 | 0.9913 | 0.9825 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9760.002 | 0.8444 | 0.6863 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9760.002 | 0.4856 | -0.0352 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9760.002 | 0.1501 | -0.7051 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9760.002 | 0.1469 | -0.7113 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9760.002 | 0.1580 | -0.6894 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9760.002 | 0.2708 | -0.4649 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10127.002 | 1.0760 | 1.2327 | 0.6658 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10127.002 | 1.1598 | 1.4989 | 0.6658 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10127.002 | 1.0565 | 1.1722 | 0.6658 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10127.002 | 1.0323 | 1.0979 | 0.6658 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 10127.002 | 0.7651 | 0.3377 | 0.6658 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 10127.002 | 0.3219 | -0.6355 | 0.6658 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 10127.002 | 0.2679 | -0.7233 | 0.6658 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 10127.002 | 0.3002 | -0.6718 | 0.6658 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 10127.002 | 0.3493 | -0.5879 | 0.6658 |