Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 7905.002 | 0.1614 | -0.9740 | 0.4198 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 7905.002 | 0.0596 | -0.9976 | 0.4198 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 7905.002 | 0.0734 | -0.9960 | 0.4198 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 7905.002 | 0.0865 | -0.9941 | 0.4198 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 7905.002 | 0.1029 | -0.9911 | 0.4198 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7906.002 | 0.7139 | 0.1113 | 0.5736 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7906.002 | 1.2035 | 1.7622 | 0.5736 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7906.002 | 0.7830 | 0.3055 | 0.5736 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7906.002 | 1.1319 | 1.4823 | 0.5736 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 7906.002 | 0.2453 | -0.8274 | 0.5736 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 7906.002 | 0.0719 | -0.9797 | 0.5736 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 7906.002 | 0.0792 | -0.9759 | 0.5736 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 7906.002 | 0.0909 | -0.9694 | 0.5736 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 7906.002 | 0.4075 | -0.5818 | 0.5736 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7907.002 | 0.7826 | 0.7156 | 1.5984 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7907.002 | 1.0632 | 1.0782 | 1.5984 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7907.002 | 0.9245 | 0.9041 | 1.5984 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7907.002 | 0.6062 | 0.4623 | 1.5984 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 7907.002 | 0.1495 | -0.3910 | 1.5984 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 7907.002 | 0.0524 | -0.6840 | 1.5984 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 7907.002 | 0.0565 | -0.6686 | 1.5984 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 7907.002 | 0.0916 | -0.5517 | 1.5984 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 7907.002 | 0.0964 | -0.5372 | 1.5984 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9759.002 | 1.0120 | 1.0211 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9759.002 | 1.0855 | 1.1501 | 1.1336 |