Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 10139.002 | 0.3136 | -0.4714 | 0.8715 | |
| SUM1315MO2 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 10139.002 | 0.3524 | -0.3957 | 0.8715 | |
| SUM149PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9830.002 | 1.0210 | 1.0217 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9830.002 | 1.1374 | 1.1383 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9830.002 | 0.9100 | 0.9044 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9830.002 | 0.3824 | 0.2138 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 9830.002 | 0.3261 | 0.1176 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 9830.002 | 0.2156 | -0.0985 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 9830.002 | 0.1785 | -0.1828 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 9830.002 | 0.2439 | -0.0390 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 9830.002 | 0.3727 | 0.1979 | 1.9252 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7918.002 | 0.9929 | 0.9950 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7918.002 | 1.1487 | 1.1001 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7918.002 | 1.1051 | 1.0717 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7918.002 | 0.7210 | 0.7822 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 7918.002 | 0.2809 | 0.2785 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 7918.002 | 0.1003 | -0.1107 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 7918.002 | 0.0710 | -0.2124 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 7918.002 | 0.1156 | -0.0649 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 7918.002 | 0.1130 | -0.0723 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9844.002 | 1.0042 | 1.0034 | 2.4608 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9844.002 | 1.0492 | 1.0394 | 2.4608 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9844.002 | 0.9887 | 0.9908 | 2.4608 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9844.002 | 0.4497 | 0.4454 | 2.4608 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 9844.002 | 0.1171 | -0.1634 | 2.4608 |