Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7505.05 | 0.1497 | -0.7555 | 0.9037 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7505.05 | 0.0951 | -0.8520 | 0.9037 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7505.05 | 0.1548 | -0.7463 | 0.9037 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7894.05 | 0.9588 | 0.8924 | 0.7608 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7894.05 | 0.9509 | 0.8720 | 0.7608 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7894.05 | 1.0152 | 1.0402 | 0.7608 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7894.05 | 0.9198 | 0.7919 | 0.7608 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7894.05 | 0.2177 | -0.7304 | 0.7608 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7894.05 | 0.2392 | -0.6949 | 0.7608 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7894.05 | 0.2369 | -0.6988 | 0.7608 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7894.05 | 0.1901 | -0.7744 | 0.7608 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7894.05 | 0.1750 | -0.7977 | 0.7608 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7895.05 | 1.0301 | 1.0546 | 1.1017 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7895.05 | 1.0033 | 1.0060 | 1.1017 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7895.05 | 0.9899 | 0.9817 | 1.1017 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7895.05 | 0.9516 | 0.9120 | 1.1017 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7895.05 | 0.1291 | -0.6881 | 1.1017 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7895.05 | 0.1443 | -0.6550 | 1.1017 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7895.05 | 0.1676 | -0.6049 | 1.1017 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7895.05 | 0.1086 | -0.7335 | 1.1017 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7895.05 | 0.1707 | -0.5982 | 1.1017 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7896.04 | 1.0606 | 1.1123 | 1.0776 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7896.04 | 1.0293 | 1.0544 | 1.0776 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7896.04 | 1.0780 | 1.1443 | 1.0776 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7896.04 | 1.0043 | 1.0080 | 1.0776 |