Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13546.174 | 0.9311 | 0.8848 | 1.2035 | |
| HCC202 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13135.174 | 0.9350 | 0.7599 | 0.5256 | |
| HCC202 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13135.174 | 0.9320 | 0.7493 | 0.5256 | |
| HCC202 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13135.174 | 0.9233 | 0.7181 | 0.5256 | |
| HCC202 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13135.174 | 0.9470 | 0.8031 | 0.5256 | |
| HCC202 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13135.174 | 0.8875 | 0.5936 | 0.5256 | |
| HCC202 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13135.174 | 0.6634 | -0.0841 | 0.5256 | |
| HCC202 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13135.174 | 0.8663 | 0.5220 | 0.5256 | |
| HCC202 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13135.174 | 0.8624 | 0.5089 | 0.5256 | |
| HCC202 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13135.174 | 0.4821 | -0.5009 | 0.5256 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12939.174 | 0.9321 | 0.6327 | 0.3466 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12939.174 | 0.9687 | 0.8248 | 0.3466 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12939.174 | 0.9348 | 0.6462 | 0.3466 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12939.174 | 0.9525 | 0.7379 | 0.3466 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12939.174 | 0.7237 | -0.2134 | 0.3466 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12939.174 | 0.7787 | -0.0281 | 0.3466 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12939.174 | 0.8871 | 0.4154 | 0.3466 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12939.174 | 0.8263 | 0.1534 | 0.3466 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12939.174 | 0.4044 | -0.8533 | 0.3466 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13583.174 | 1.0322 | 1.1815 | 0.3654 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13583.174 | 1.0100 | 1.0550 | 0.3654 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13583.174 | 0.9976 | 0.9871 | 0.3654 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13583.174 | 1.0551 | 1.3165 | 0.3654 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13583.174 | 0.7774 | 0.0040 | 0.3654 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13583.174 | 0.6968 | -0.2559 | 0.3654 |