Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13583.174 | 0.8480 | 0.2738 | 0.3654 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13583.174 | 0.8052 | 0.1054 | 0.3654 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13583.174 | 0.0004 | -1.0000 | 0.3654 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13733.174 | 0.9533 | 0.8206 | 0.5093 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13733.174 | 0.9627 | 0.8560 | 0.5093 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13733.174 | 0.9845 | 0.9395 | 0.5093 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13733.174 | 0.9629 | 0.8569 | 0.5093 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13733.174 | 0.8653 | 0.5053 | 0.5093 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13733.174 | 0.8773 | 0.5467 | 0.5093 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13733.174 | 0.9011 | 0.6301 | 0.5093 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13733.174 | 0.9267 | 0.7223 | 0.5093 | |
| HCC3153 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13733.174 | 0.8917 | 0.5971 | 0.5093 | |
| HCC38 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12617.174 | 0.9473 | 0.9332 | 1.5935 | |
| HCC38 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12617.174 | 0.9985 | 0.9981 | 1.5935 | |
| HCC38 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12617.174 | 1.0130 | 1.0163 | 1.5935 | |
| HCC38 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12617.174 | 1.0036 | 1.0045 | 1.5935 | |
| HCC38 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12617.174 | 0.9682 | 0.9598 | 1.5935 | |
| HCC38 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12617.174 | 0.3091 | -0.0427 | 1.5935 | |
| HCC38 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12617.174 | 0.6848 | 0.5770 | 1.5935 | |
| HCC38 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12617.174 | 0.6018 | 0.4542 | 1.5935 | |
| HCC38 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12617.174 | 0.1208 | -0.4690 | 1.5935 | |
| HCC70 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12714.174 | 0.9506 | 0.7157 | 0.3306 | |
| HCC70 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12714.174 | 0.9444 | 0.6824 | 0.3306 | |
| HCC70 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12714.174 | 0.9508 | 0.7171 | 0.3306 | |
| HCC70 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12714.174 | 0.9721 | 0.8361 | 0.3306 |