Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12662.176 | 0.9543 | 0.9491 | 1.8146 | |
| MDA-MB-134-VI | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12662.176 | 0.9505 | 0.9448 | 1.8146 | |
| MDA-MB-134-VI | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 12662.176 | 0.9803 | 0.9782 | 1.8146 | |
| MDA-MB-134-VI | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 12662.176 | 0.9350 | 0.9272 | 1.8146 | |
| MDA-MB-134-VI | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 12662.176 | 0.9237 | 0.9145 | 1.8146 | |
| MDA-MB-157 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12632.176 | 0.9868 | 0.9674 | 0.8098 | |
| MDA-MB-157 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12632.176 | 0.9636 | 0.9104 | 0.8098 | |
| MDA-MB-157 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12632.176 | 0.9941 | 0.9854 | 0.8098 | |
| MDA-MB-157 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12632.176 | 1.0033 | 1.0081 | 0.8098 | |
| MDA-MB-157 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12632.176 | 0.9921 | 0.9805 | 0.8098 | |
| MDA-MB-157 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12632.176 | 0.9773 | 0.9440 | 0.8098 | |
| MDA-MB-157 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.133 | uM | 12632.176 | 0.9790 | 0.9481 | 0.8098 | |
| MDA-MB-157 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.667 | uM | 12632.176 | 1.0557 | 1.1383 | 0.8098 | |
| MDA-MB-157 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 3.33 | uM | 12632.176 | 0.9401 | 0.8532 | 0.8098 | |
| MDA-MB-175-VII | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13754.176 | 0.9485 | 0.8548 | 0.7009 | |
| MDA-MB-175-VII | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13754.176 | 0.9344 | 0.8155 | 0.7009 | |
| MDA-MB-175-VII | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13754.176 | 0.9330 | 0.8117 | 0.7009 | |
| MDA-MB-175-VII | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13754.176 | 0.9770 | 0.9346 | 0.7009 | |
| MDA-MB-175-VII | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13754.176 | 0.9399 | 0.8306 | 0.7009 | |
| MDA-MB-175-VII | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13754.176 | 0.9620 | 0.8925 | 0.7009 | |
| MDA-MB-175-VII | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 13754.176 | 0.9727 | 0.9226 | 0.7009 | |
| MDA-MB-175-VII | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 13754.176 | 0.9555 | 0.8742 | 0.7009 | |
| MDA-MB-175-VII | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 13754.176 | 0.9238 | 0.7861 | 0.7009 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12989.176 | 0.9925 | 0.9812 | 0.7997 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12989.176 | 0.9900 | 0.9750 | 0.7997 |