Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 13091.176 | 1.0056 | 1.0127 | 0.8746 | |
| 600MPE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 13091.176 | 0.9909 | 0.9792 | 0.8746 | |
| 600MPE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 13091.176 | 0.9876 | 0.9717 | 0.8746 | |
| AU565 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13030.176 | 0.9450 | 0.8887 | 0.9892 | |
| AU565 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13030.176 | 0.9900 | 0.9798 | 0.9892 | |
| AU565 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13030.176 | 1.0273 | 1.0552 | 0.9892 | |
| AU565 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13030.176 | 1.0370 | 1.0749 | 0.9892 | |
| AU565 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13030.176 | 1.0661 | 1.1337 | 0.9892 | |
| AU565 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13030.176 | 0.9980 | 0.9959 | 0.9892 | |
| AU565 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 13030.176 | 1.0191 | 1.0386 | 0.9892 | |
| AU565 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 13030.176 | 0.9103 | 0.8188 | 0.9892 | |
| AU565 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 13030.176 | 0.9530 | 0.9050 | 0.9892 | |
| BT-20 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13579.176 | 1.0469 | 1.1227 | 0.7690 | |
| BT-20 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13579.176 | 1.0464 | 1.1214 | 0.7690 | |
| BT-20 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13579.176 | 1.0551 | 1.1445 | 0.7690 | |
| BT-20 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13579.176 | 1.1392 | 1.3694 | 0.7690 | |
| BT-20 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13579.176 | 0.9855 | 0.9623 | 0.7690 | |
| BT-20 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13579.176 | 0.9937 | 0.9835 | 0.7690 | |
| BT-20 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.133 | uM | 13579.176 | 0.9794 | 0.9467 | 0.7690 | |
| BT-20 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.667 | uM | 13579.176 | 1.0059 | 1.0154 | 0.7690 | |
| BT-20 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 3.33 | uM | 13579.176 | 0.9550 | 0.8837 | 0.7690 | |
| BT-474 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13125.176 | 1.0072 | 1.0171 | 0.8351 | |
| BT-474 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13125.176 | 0.9617 | 0.9086 | 0.8351 | |
| BT-474 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13125.176 | 0.9923 | 0.9817 | 0.8351 | |
| BT-474 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13125.176 | 1.0255 | 1.0613 | 0.8351 |