Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7849.043 | 1.0137 | 1.0794 | 0.3502 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7849.043 | 0.9403 | 0.6775 | 0.3502 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7849.043 | 0.9005 | 0.4825 | 0.3502 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7849.043 | 0.5671 | -0.6042 | 0.3502 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7849.043 | 0.3670 | -0.8857 | 0.3502 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 9421.034 | 0.9724 | 0.9121 | 0.6220 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 9421.034 | 0.9675 | 0.8967 | 0.6220 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 9421.034 | 0.9976 | 0.9923 | 0.6220 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 9421.034 | 0.8994 | 0.6867 | 0.6220 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 9421.034 | 0.7350 | 0.2192 | 0.6220 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 9421.034 | 0.4816 | -0.3821 | 0.6220 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 9421.034 | 0.2767 | -0.7465 | 0.6220 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 9421.034 | 0.1443 | -0.9110 | 0.6220 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 9421.034 | 0.0089 | -0.9990 | 0.6220 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 10263.034 | 1.0546 | 1.3043 | 0.3750 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 10263.034 | 0.9305 | 0.6505 | 0.3750 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 10263.034 | 0.9436 | 0.7130 | 0.3750 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 10263.034 | 0.9144 | 0.5754 | 0.3750 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 10263.034 | 0.7596 | -0.0391 | 0.3750 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 10263.034 | 0.5309 | -0.6303 | 0.3750 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 10263.034 | 0.2842 | -0.9302 | 0.3750 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 10263.034 | 0.1296 | -0.9914 | 0.3750 | |
| HCC2185 | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 10263.034 | 0.0057 | -1.0000 | 0.3750 | |
| HCC3153 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7853.007 | 1.0933 | 1.1382 | 1.3351 | |
| HCC3153 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7853.007 | 0.9754 | 0.9631 | 1.3351 |