Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13125.176 | 0.9987 | 0.9969 | 0.8351 | |
| BT-474 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13125.176 | 0.9903 | 0.9768 | 0.8351 | |
| BT-474 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 13125.176 | 1.0031 | 1.0073 | 0.8351 | |
| BT-474 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 13125.176 | 0.9990 | 0.9976 | 0.8351 | |
| BT-474 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 13125.176 | 0.9471 | 0.8740 | 0.8351 | |
| BT-483 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13130.176 | 0.9559 | 0.8257 | 0.4942 | |
| BT-483 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13130.176 | 0.9357 | 0.7484 | 0.4942 | |
| BT-483 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13130.176 | 0.9446 | 0.7822 | 0.4942 | |
| BT-483 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13130.176 | 0.9787 | 0.9148 | 0.4942 | |
| BT-483 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13130.176 | 0.9504 | 0.8043 | 0.4942 | |
| BT-483 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13130.176 | 0.9480 | 0.7950 | 0.4942 | |
| BT-483 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 13130.176 | 0.9577 | 0.8325 | 0.4942 | |
| BT-483 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 13130.176 | 0.9611 | 0.8457 | 0.4942 | |
| BT-483 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 13130.176 | 0.9536 | 0.8165 | 0.4942 | |
| BT-549 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12690.176 | 0.9417 | 0.9503 | 2.3892 | |
| BT-549 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12690.176 | 0.9529 | 0.9600 | 2.3892 | |
| BT-549 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12690.176 | 0.9988 | 0.9990 | 2.3892 | |
| BT-549 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12690.176 | 0.9791 | 0.9824 | 2.3892 | |
| BT-549 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12690.176 | 0.9555 | 0.9623 | 2.3892 | |
| BT-549 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12690.176 | 0.9757 | 0.9795 | 2.3892 | |
| BT-549 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.133 | uM | 12690.176 | 0.9625 | 0.9683 | 2.3892 | |
| BT-549 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.667 | uM | 12690.176 | 0.9643 | 0.9698 | 2.3892 | |
| BT-549 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 3.33 | uM | 12690.176 | 0.8822 | 0.8978 | 2.3892 | |
| CAMA-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12647.176 | 0.9686 | 0.9360 | 0.9797 | |
| CAMA-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12647.176 | 0.9576 | 0.9136 | 0.9797 |