Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12647.176 | 0.9836 | 0.9666 | 0.9797 | |
| CAMA-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12647.176 | 1.0058 | 1.0118 | 0.9797 | |
| CAMA-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12647.176 | 1.0092 | 1.0188 | 0.9797 | |
| CAMA-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12647.176 | 0.9587 | 0.9157 | 0.9797 | |
| CAMA-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 12647.176 | 0.9939 | 0.9875 | 0.9797 | |
| CAMA-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 12647.176 | 0.9591 | 0.9165 | 0.9797 | |
| CAMA-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 12647.176 | 0.9364 | 0.8702 | 0.9797 | |
| HCC1143 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13099.176 | 0.9332 | 0.8799 | 1.1168 | |
| HCC1143 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13099.176 | 1.0648 | 1.1158 | 1.1168 | |
| HCC1143 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13099.176 | 1.0175 | 1.0313 | 1.1168 | |
| HCC1143 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13099.176 | 0.9531 | 0.9158 | 1.1168 | |
| HCC1143 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13099.176 | 0.9946 | 0.9903 | 1.1168 | |
| HCC1143 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13099.176 | 0.9510 | 0.9120 | 1.1168 | |
| HCC1143 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.133 | uM | 13099.176 | 0.9758 | 0.9565 | 1.1168 | |
| HCC1143 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.667 | uM | 13099.176 | 0.9011 | 0.8219 | 1.1168 | |
| HCC1143 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 3.33 | uM | 13099.176 | 0.9585 | 0.9255 | 1.1168 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12696.176 | 0.9394 | 0.7839 | 0.5469 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12696.176 | 0.9462 | 0.8077 | 0.5469 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12696.176 | 0.9355 | 0.7705 | 0.5469 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12696.176 | 0.9860 | 0.9491 | 0.5469 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12696.176 | 0.9830 | 0.9382 | 0.5469 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12696.176 | 0.9302 | 0.7523 | 0.5469 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.133 | uM | 12696.176 | 0.9560 | 0.8420 | 0.5469 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.667 | uM | 12696.176 | 0.9443 | 0.8009 | 0.5469 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 3.33 | uM | 12696.176 | 0.8982 | 0.6436 | 0.5469 |